It also loads the roms instantly now. So you dont have to wait for it to write it like the V1.
I bet this will fix the issues V1 had with some types of region modifications.
I just put a region mod in a Turbo Duo for seieienbu and it would not work with the Everdrive v1. It was giving a black screen after loading a few roms I tested and Keith Courage would give a black screen after pressing run. The v2 runs with no issues though.
This is the circuit I used, which worked fine with the v1 the other couple times I used it so far:
https://www.pcenginefx.com/forums/index.php?topic=8732.msg170853#msg170853