There are way to many suited to board games. All the sims pretty much. Populous would be cool. A vertical gane based on Panic Bomber might work. Shelock Holmes could be extremely faithful, especially with vhs tape gameplay included.
Didn't they release a DVD version or something like that of Sherlock Holmes?
Yes, I have it and played it. If the DVD controls were a bit more fun-to-use -->responsive<-- (it's just the nature of navigating DVD menus) it would be AWESOME. OK, I'm exaggerating. It's not bad. Controls lag a bit, but the video/sound quality is 1,000x better than TG-CD or Sega-CD versions.
--> Sadly, the improved video quality reveals the "cheap" sets and costumes...the grainy, compressed video in TG-CD/Sega-CD actually made the segments more "authentic" and "genuine", if you can believe that.
I also have Dracula Unleashed on DVD (same deal as Sherlock Holmes), but I never finished it.