The top for me is Lunar: The Silver Star (Sega CD).
Others are Super Mario Bros/DH, Golden Axe, Mega Man 2, Sonic the Hedgehog, Zelda: A Link to the Past, Metroid, Ys I&II, Bonk's Adventure, Life Force/Salamander, Super Mario World, Super Mario Bros. 3, Civilization, Sim City 2000, Dragon Force, Parodius Da!, F-Zero, Final Fantasy VI, Chrono Trigger, so many more...