Other than something like Super Mario Kart that relies heavily on mode 7 effects, most anything could be ported to the PCE with varying degrees of accuracy. The gameplay itself could be spot on, but the color depth, parallax scrolling, and stuff like transparencies would need to be toned down and/or done differently (i.e. - dithering, sprites to fake a second scroll layer, sprite animation in place of scaling/rotation, etc.).