Welcome to the club. Sounds like some caps need replacing. I've not dealt with a "RF" unit briefcase before, but I'm sure Blue, Chop or the others will have some info for ya (in case there is not a tread already). I figure the interface unit is where it issues lay, but sound issues are normally associated with CD Redbook.
I had a Duo on the bench last week that had crackling audio. I replace the common sound caps and it seemed to make it 95% better...since it's not my Duo, I was not gonna attempt a complete capacitor replacement. My personal Duo seems to have lost all ADPCM, but I have a replacement m5205 coming and I hope that solves it. Welcome to the club where everything breaks.