While continuing to diagnose I developed a direct short somewhere that fries fuses on power up. In the mean time I purchased a slightly beat up DUO from KC and just swapped my nicer shell to it.
Uh-oh, watch out, that's what happened with my SNES... The great Steve called it right in my case, but I learned too late before he could help me. One of your voltage regulators is possibly dying! I thought it was just "surges" and ran out of 1-2 amp fuses, used 3 amps, but it happened again and that's how I damaged one of the SRAM chips (High voltage got sent into the motherboard, I should've waited for my order of 1 amp fuses to arrive!). Then it wouldn't turn on at all, so I ultimately thought to desolder the 7805 regulator and do a 5 Volt mod bypass with a well-regulated power supply, so now it's like the USB standard running direct on a 5 VDC supply. Plug contacts have to be REALLY clean though. While I got the unit running again, it was not without graphical glitches due to permanent damage...
Anyway, continuous blowing of fuses on power up even at 2 amps (I know we talked about sticking with 1 if possible) could indicate one of the regulators is going bad and will die completely. You have a 5 Volt and a 8 Volt together, so I'd investigate the possibility that one of them is going bad. If you did nothing major when this started to occur, it was working, then all of a sudden it started doing this, then yeah, I'd look at that. If you did even more solder work after that chip, then maybe you caused the short, but if it just happened all of a sudden on a running unit albeit with minor sound problems, perhaps a regulator is going bonkers (and continuous blowing of fuses is an indicator).
P.S. *minibreaker over one-time fuses = cool.