Thanks for all the input all! I know I am ultimately going to go with a Duo-R with a switch and Arcade Card. I want to own one too much to pass it up! But I have decided today to start my retro gaming collection with an all-in-one system: the Cyber Gadget Retro Freak. I don't have much space and am working with a teacher's salary. So, having 14 consoles under one roof is helpful.
It does TG16, PCE, and PCE Super Graphics, along with NES (through adapter), Famicom, SNES, Super Famicom, Genesis, Mega Drive, Mk III (through adapter), Sega Master System (through adapter), GB, GBC, and GBA... And all Roms for each as well via SD Card. Then it spits it out in 720p with various filters and the ability to add in scan lines. It's pretty sweet if you're not a purist. All of this for about $200. Check it out if you haven't seen it! Reviews are quite good and there are plenty where you can see gameplay for each console it boasts!
I will get the Duo-R after I have about $700 to drop on it. But, until then I will at least be able to play all but the CD games!