The TG16 desperately needed more licensed tie-in games, to compete with the NES. Boomer parents were buying NES consoles because of Back to the Future, Ghostbusters and Jaws games, not original titles like The Guardian Legend or Crystalis.
That said, what I would have loved to see is a Teenage Mutant Ninja Turtles game for the TG16. Given Konami did eventually put out some PC Engine games, I don't see why they couldn't have done a TMNT game for it, unless their TMNT contract restricted games to only Nintendo systems...