The main problem with CDR's in Duo's is the Duo itself. The Duo is cheaply made, and very likely to fail on you at one time or another, whether you use CDR's in it or not. I have 3 of them, and they have all crapped out at one time or another. Even the one I bought new from Telegames 5 years ago, with less than 20 hours TOTAL play time on it, quit working. No way I'd send it to Retrogames, and pay them $65 to swap my dead one for one of their refurbished ones. Try calling game stores, and electronic shops around your area first. Theres a place called Games N More here close by that does system repairs, and even though they had never repaired a Duo, he was willing to take a look at it, and figured out the problem. Long as its not an exclusive component, or something you can't get anywhere, you might get lucky. So, now I have all my Duo's working, but I'll stick with my original CD unit. Its never failed me.